Enabling Cures
Primate research has been responsible for countless medical breakthroughs that save and improve human lives.
“We need dependable supply of high quality models to ensure we can maintain our client’s timelines and produce effective study outcomes.”
– Contract Research Organization (CRO)
“Given escalating pricing, we have had to deprioritize new drug candidates. Without a solution, it will definitely impact our ability to bring new therapies to those who desperately need them.”
– Large Pharma Client
“There is a clear need for a Specific Pathogen Free (SPF) domestically bred primate to increase model quality and serve as a safeguard against frequent supply chain disruptions.”
– Mid-Size Pharma
“There are no alternative approaches that can replace nonhuman primate (NHP) models to answer research questions that require complete multiorgan interactions and integrated biology. Thus, NHPs continue to be essential.”
– National Academies of Sciences, Engineering, and Medicine. 2023 Report to NIH
“Given the nation’s most pressing public health needs and the evolving state of the science, specific domains of research—including neuroscience and neurodegenerative disorders, preparedness for unanticipated communicable infectious threats, immunotherapy, reproduction, aging, and chronic inflammatory diseases—are likely to require increased use of nonhuman primates in the future.”
– National Academies of Sciences, Engineering, and Medicine. 2023 Report to NIH
“We need dependable supply of high quality models to ensure we can maintain our clients timelines and produce effective study outcomes.”
– Contract Research Organization (CRO)
“Given escalating pricing, we have had to deprioritize new drug candidates. Without a solution, it will definitely impact our ability to bring new therapies to those who desperately need them.”
– Large Pharma Client
“There is a clear need for a Specific Pathogen Free (SPF) domestically bred primate to increase model quality and serve as a safeguard against frequent supply chain disruptions.”
– Mid-Size Pharma
“There are no alternative approaches that can replace nonhuman primate (NHP) models to answer research questions that require complete multiorgan interactions and integrated biology. Thus, NHPs continue to be essential.”
– National Academies of Sciences, Engineering, and Medicine. 2023 Report to NIH
“Given the nation’s most pressing public health needs and the evolving state of the science, specific domains of research—including neuroscience and neurodegenerative disorders, preparedness for unanticipated communicable infectious threats, immunotherapy, reproduction, aging, and chronic inflammatory diseases—are likely to require increased use of nonhuman primates in the future.”
– National Academies of Sciences, Engineering, and Medicine. 2023 Report to NIH
Primate Research: By the Numbers
335 Million
The number of Americans who will use life-saving drugs in their lifetime
0.5%
Primate usage as a percentage of all animal models used in research
568
New Drugs approved over the last 10 years where primates played a critical role in their development
Top 20 Drugs Developed via Primate Research
DRUG LOGOS ARE NOT AN IMPLIED ENDORESEMENT OF SHM BY THE MANUFACTERERS OF THESE DRUGS AND ARE NOT INTENDED TO IMPLY ENDORSEMENT. LOGOS ARE ONLY MEANT TO INFORM WHAT DRUGS HAVE RELIED UPON NHPS FOR RESEARCH.
Critical Role Primates Play in Research
Discovering New
Life-Saving Therapies
Many breakthroughs in medical research have been made possible thanks to the use of primate models. Our goal is to provide researchers with healthy primates, living in clean and humane conditions, to facilitate scientific advancements. We understand the importance of animal welfare, which is why we prioritize our primates’ well-being by providing them with exercise areas, a balanced diet, and a stress-free environment. We work closely with researchers to ensure that their work is not just effective but also ethical.
Protecting Your Safety
As a leading provider of primate models for preclinical testing, we understand the importance of proving drug safety before moving on to human trials. Primate models have proven to be superior due to their genetic similarities to humans, which allows for more accurate predictions of human reactions to certain drugs.
Advancing Research Required by Regulation
As a Regulatory Requirement in developing most new drugs, the FDA mandates the primate model for many new candidates to ensure the safety of new therapies. By testing on primates, scientists can obtain accurate and reliable data that is impossible to acquire through other methods. This research guarantees that new treatments will not harm humans.
What Matters to Us
Animal Welfare
Cures
Value
Innovation
Trust
Community
Animal Welfare – Our Top Priority
We cherish the primates under our care and are committed to providing exceptional care and attention to each primate in our facility. Our animal welfare program has been developed to ensure the necessary environment so that each primate in our care is happy, healthy, and well-treated. Our expert staff and leading veterinarians ensure that the care our primates provide an environment where they will thrive and can fulfill their important role in developing new, innovative medicines.
Cures – Meaningful Work
It isn’t just about creating quality jobs with strong pay. We are about creating a team environment where each member can contribute to making a real difference in the development of new therapies that will positively impact our families, friends and society.
Value – Client Solutions
We believe that every client is unique and requires a tailored approach. We take the time to listen and understand your research needs, then develop innovative solutions that will help you achieve your research objectives. Trust us to provide high-quality primates and tailored services that meet your specific requirements.
Innovation – Creative Solutions
We are committed to providing the highest level of care for our primates and service for our clients. Our experienced staff is constantly working to improve our programs and services to meet evolving needs. With a focus on continuous training and investment in the latest tools and techniques, we strive to create value and exceed your expectations every step of the way.
Trust – Doing It Right
We believe in conducting business with transparency, ethics, and respect. We are dedicated to meeting our customers’ needs in a way that is both ethical and sustainable. We understand the importance of supporting our team members and taking care of our environment, and we are committed to doing so every step of the way.
Community – Local Partners
Community partnerships are important to us, and we are committed to our community’s success. We prioritize working with local organizations and to support philanthropic causes, education, the environment, and the local economy. Our focus on contributing toward a stronger community is integral to our mission and helping create a brighter future.
Animal Welfare – Our Top Priority
We cherish the primates under our care and are committed to providing exceptional care and attention to each primate in our facility. Our animal welfare program has been developed to ensure the necessary environment so that each primate in our care is happy, healthy, and well-treated. Our expert staff and leading veterinarians ensure that the care our primates provide an environment where they will thrive and can fulfill their important role in developing new, innovative medicines.
Cures – Meaningful Work
It isn’t just about creating quality jobs with strong pay. We are about creating a team environment where each member can contribute to making a real difference in the development of new therapies that will positively impact our families, friends and society.
Value – Client Solutions
We believe that every client is unique and requires a tailored approach. We take the time to listen and understand your research needs, then develop innovative solutions that will help you achieve your research objectives. Trust us to provide high-quality primates and tailored services that meet your specific requirements.
Innovation – Creative Solutions
We are committed to providing the highest level of care for our primates and service for our clients. Our experienced staff is constantly working to improve our programs and services to meet evolving needs. With a focus on continuous training and investment in the latest tools and techniques, we strive to create value and exceed your expectations every step of the way.
Trust – Doing it Right
We believe in conducting business with transparency, ethics, and respect. We are dedicated to meeting our customers’ needs in a way that is both ethical and sustainable. We understand the importance of supporting our team members and taking care of our environment, and we are committed to doing so every step of the way.
Community – Local Partners
Community partnerships are important to us, and we are committed to our community’s success. We prioritize working with local organizations and to support philanthropic causes, education, the environment, and the local economy. Our focus on contributing toward a stronger community is integral to our mission and helping create a brighter future.
Frequently Asked Questions
After reviewing 13 sites in 6 different states, we wanted to highlight the attractive features that impacted our decision to select Bainbridge and Decatur County as the future home for Safer Human Medicine. Some key elements include:
Community
● Vibrant and growing community with an attractive downtown and commitment to investing for the future
● Affordable housing, strong school systems, and a wide choice of recreational activities
● Strong workforce within a 60-minute radius that is supportive of animals and their important role in everyday life
● Desire for high paying jobs to retain workforce within the county
● During our diligence, we met with many people from the community who were pleasant and inviting, giving us a positive feel for the community
Education
● Technical college training and internship programs in veterinary and animal husbandry
● Partnerships with high school and business to incorporate skills needed for future employment
● Employee training assistance willing to custom design programs to support business needs
● 3 veterinary schools within a 4-hour drive
Infastructure
● Committed investment in roadways, municipal systems, and availability of all necessary utilities
Location
● Proximity to airports and major interstates and highways for ease of access
● Warm climate which closely resembles a primate’s natural environment
● Low risk zone for severe weather events
Business Partnership
● An Economic Development Council extremely innovative in targeting industries that are trying to address U.S. supply chain needs
● Local business support/partnership (hotels, restaurants, produce, animal feed/bedding, equipment)
● Vast number of construction contractors in the area
All animals brought to our site will be from farms that have bred them in captivity. The risk of these animals carrying any disease is extremely low given the continuous screening practices outlined in the following:
- These animals are tested for known viruses that can be found in the primate species starting shortly after birth. They are then tested again at weaning. We routinely audit international suppliers for adherence to testing programs and welfare and known health quality.
- A minimum of 30 days prior to shipment to SHM, the primates will go through a full quarantine where they are tested again. The 30 days is also defined by CDC as sufficient based on incubation periods required to demonstrate symptoms.
- Once the animals arrive at our site, they go through a defined CDC quarantine period of at least another 30 days which is monitored by the CDC. We also do numerous additional tests that exceed what is required by the CDC.
- We will continue to perform regular testing to ensure the full health of our animals while on site.
- If an animal dies while in our facilities, there is routine veterinarian reviews (necropsy) to determine cause of death and the animals are managed according to biosecurity procedures until it is removed from our site by a certified third party who follows defined biosecurity procedures for medical waste incineration.
It is critical that the animals on our site are virus and pathogen free to ensure they produce quality study outcomes. We take great strides in our facility design to ensure animals are protected from exposure to any source of diseases. In the photos below, you will see 1) our facility perimeter will be fenced to prevent any of the native wildlife from accessing our operations, and 2) the exterior of our buildings will be shielded with high tensile screens that prevent access from rodents, insects, and birds.
The NHPs we import are all from purpose-bred colonies and are not animals being taken from the wild. These purpose-bred animals are routinely screened after birth, during grow-out, and prior to importation to the U.S. Once in the U.S., they are further screened multiple times as part of a highly regulated CDC Quarantine process. Our veterinary and animal care staff will closely monitor the health of the NHPs under our care after quarantine release. Because of these stringent requirements, the risk of spreading disease is extremely low.
In the unlikely event that an animal tests positive for a disease, it would be humanely euthanized and removed from our site by a certified third party who follows defined biosecurity procedures for medical waste incineration.
The NHPs at SHM’s facilities will be housed in large animal enclosures inside our secure buildings. These enclosures are not only designed to make the NHPs under our care feel safe and comfortable, but also to prevent escape. Our facilities are built to give NHP’s access to the outside air and sunlight they enjoy. Our facility has several safeguards to prevent escape, including a unique building design that incorporates double barriers throughout each building. In the unlikely event an animal gets out of its enclosure, our building design will not permit two doors leading to the exterior to be opened simultaneously, preventing an animal from getting out of the building.
Animal Welfare, including preventing escape, is a top priority and has heavily influenced our facility’s design. As a result, we have engineered into our buildings multiple redundancies. The following outlines how our animals will remain in safe surroundings in the event any one specific design feature is compromised.
- Our buildings are engineer rated to withstand a direct Category 4 Hurricane. We will keep trees around the site perimeter, but we will not have tall trees near the animal buildings or fencing.
- Our buildings are designed to allow air to pass through which helps equalize the pressure within the building. This will greatly reduce the risk of a roof being lifted off in a storm event.
- In the unlikely event that a roof is compromised, or a projectile penetrates the outer screen, the pens that the NHPs are housed in are constructed of sturdy stainless steel anchored into cinderblock walls. This means the pens are a secondary enclosure within the buildings.
- All exits have double barrier door systems with mechanisms that prevent two doors from being open at the same time, which significantly reduces the risk of escape.
- We will have a proven perimeter fencing design that includes non-harmful electrification. This will serve as an additional safeguard against escape and will also deter wildlife from entering our property
There are several facilities comparable to ours, including in Georgia, located within a few hundred yards of neighborhoods and schools. This provides strong evidence that noise and smell are not a nuisance to local residents.
The noise level of our operation will be significantly less than a manufacturing operation you would typically see in an industrial park. This is a day-shift operation that will mirror other agricultural facilities in the area. On average, starting time will be around 6:30-7:00 am and the day typically ends by 3:30pm.
These NHPs are not large. On average, they are approximately 6-7 pounds (roughly the size of a house cat). Cynomolgus macaques make little to no noise and most sound is contained within the building.
Given their smaller size and our regular husbandry practices, we have confidence that there will be no noticeable smell coming from our site.
Nothing discharged from our facility will create an environmental hazard or risk. Most of our wastewater comes from regularly washing down our animal enclosures so that we can lay dry bedding and give our NHPs a clean space to forage, eat and play. We will work closely with the City of Bainbridge to make certain that, much like other farms, our natural animal waste is properly treated and disposed of so that it presents no environmental risk to our neighbors.
In The News
In The News
Careers The Benefits of working With SHM
Location
We chose to be in Bainbridge because it provides an ideal location with proximity to local technical colleges, access to reliable infrastructure, a business-friendly community and quality people accustomed to agriculture, science, caring for animals and the environment.
Community
Safer Human Medicine plans to invest a minimum of $270 million and potentially up to $396 million into the community.
We are planning to create approximately 260 good paying jobs beginning in 2024 with competitive wages and full benefits for every position.
Compensation
Starting compensation, including benefits, for an entry level, hourly position is $60,000 with overtime eligibility.
Starting pay and benefits will range from $60,000 (entry level) to more than $200,000 (Attending Veterinarian) across the approximately 260 jobs we create in Bainbridge.
Training
SHM is committed to supporting the local community through workforce development and training opportunities like educational partnerships, co-ops, and internships.
**CHECK THIS SITE IN THE COMING WEEKS AND MONTHS TO APPLY FOR OPEN POSITIONS!**
SHM’S ECONOMIC IMPACT DELIVERED OVER THE NEXT 10 YEARS
Jobs Created
403
277 Direct Operations
79 Construction
97 Indirect Jobs
Worker Earnings
$202M
Salary & Benefits for all jobs created over 10 years
Economic Output
$743M
Total impact for construction, SHM operations, and indirect spending by other employers
SHM’S Fiscal Tax Contribution OVER THE NEXT 10 YEARS
Local
$7.2M
$3.2 to Bainbridge
$3.6 to Decatur County
& Public Schools
State
$24.7M
$13.7M Individual Income Tax
$9.5M Sales Tax
$1.5M Corporate Income Tax
total
$32M
Total impact for construction, SHM operations, and indirect spending by other employers
SHM WILL BRIGHTEN BAINBRIDGE’S FUTURE
SHM is funding 100% of the project cost. Any incentives are reductions to future taxes and are only available if SHM achieves growth targets for the community.
Other industries will see a direct benefit from increased spending by new workers and visitors in real estate, construction, retail, hospitality, banking, entertainment, etc.
SHM’s contribution to the municipal systems will help minimize cost increases from pending bond payments.
An employment shift where residents stay in the community for work versus leaving for jobs outside of Decatur County.